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"Drug closing in on Alzheimer's"

The Australian

Source: The Australian

Published: 20 Sep 2008

Category: Pharmaceutical

Rating: (4½ stars)

what they said (Hover the mouse cursor over underlined words for more info)

BETA-amyloid protein isn't really much to look at. A tangle of amino acids, for much of our lives it exists harmlessly in our brains.

The original article can be found at: http://www.theaustralian.news.com.au/story/0,25197,24368210-23289,00.html

how did it rate? (more information)

Criteria Rating
Total Score 8 of 9
Novelty of Treatment Satisfactory (?)
Availability of Treatment Satisfactory (?)
Treatment Options Satisfactory (?)
Disease Mongering Satisfactory (?)
Evidence Satisfactory (?)
Quantification of Benefits of Treatment Not Satisfactory (?)
Harms of Treatment Satisfactory (?)
Costs of Treatment Not Applicable
Sources of Information Satisfactory (?)
Relies on Press Release Satisfactory (?)

what we said (Hover the mouse cursor over underlined words for more info)

This is more of a feature article than news. It covers in some detail the development and early human testing of a drug that is designed to deplete amyloid-â peptide Aâ42, thought by some to be a cause of Alzheimer's disease. Strong features of the article are that it goes well beyond the media release that accompanied publication of the clinical trial report in July 2008 and the cautionary note that these are very early clinical data. The article could have pointed out that this was a randomised placebo controlled trial of two doses of the experimental drug. It could also have mentioned that rates of diarrhoea and nausea were slightly higher with the experimental drug than with placebo. But overall this is good reporting containing much of what we'd like to see in health reports

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